占教授长期深耕脂质纳米药物基础与转化医学研究，在脂质纳米药物体内过程及与机体互作机制、脂质纳米药物体内个性化精准递送、脂质纳米药物质量控制与评价等领域取得了多项创新性研究成果。截止目前已申请专利23项，PCT5项，授权6项, 转化转让3项，发表SCI论文>100篇
获奖成果：2022，教育部青年科学奖
2021，国家自然科学基金杰青项目
2019，中国药学会-以岭生物医药青年奖
2018，上海市卫生计生系统优秀学科带头人
2018，第一三共制药奖教金
2017，教育部自然科学奖二等奖
2016，上海市自然科学奖二等奖
2014，中国药学会科学技术奖二等奖
代表性论文：- Wang H#,*, Lin S#, Wu X#, Jiang K, Lu H, Zhan C*. Interplay between Liposomes and IgM: Principles, Challenges, and Opportunities. Adv Sci 2023, e2301777. (IF 17.521)
- Ban Y#, Chu Y#, Pan F, Guo Z, Yang Y, Wei X, Li G, Qian J, Zhan C*, Zhang J*, Tang L*. Lipid-based Nanocarriers Enabled Oral Delivery of Oleanolic Acid Derivative DKS26 for Diabetes Management. Adv Health Mater 2023, 28, e2300639. (IF 11.092)
- Chen T#, Pan F#, Luo G#, Jiang K, Wang H, Ding T, Li W*, Zhan C*, Wei X*. Morphology-driven protein corona manipulation for preferential delivery of lipid nanodiscs. Nano Today 2022, 46, 101609. (IF 18.962)
- Wang H#, Lin S#, Wang S, Jiang Z, Ding T, Wei X, Lu Y, Yang F, Zhan C*. Folic Acid Enables Targeting Delivery of Lipodiscs by Circumventing IgM-Mediated Opsonization. Nano Lett 2022, 22, 16, 6516–6522. (IF 12.262)
- Jiang Z#, Chu Y#, Zhan C*. Protein corona: challenges and opportunities for targeted delivery of nanomedicines. Expert Opin Drug Deliv 2022, 19(7):833-846. (IF 8.129)
- Gao X*, Xu J, Yao T, Liu X, Zhang H, Zhan C*. Peptide-decorated nanocarriers penetrating the blood-brain barrier for imaging and therapy of brain diseases. Adv Drug Deliv Rev 2022, 187:114362. (IF 17.873)
- Zhang X#, Tang W#, Wen H, Wu E, Ding T, Gu J, Lv Z*, Zhan C*. Evaluation of CTB-sLip for Targeting Lung Metastasis of Colorectal Cancer. Pharmaceutics 2022, 14 (4):868. (IF 6.321)
- Jiang K, Fan X, Hu Y, Yao S, Liu Y, Zhan C*, Lu W, Wei G*. Topical instillation of cell-penetrating peptide-conjugated melphalan blocks metastases of retinoblastoma. Biomaterials 2022, 284:121493. (IF 12.479)
- Yang Y#, Long K#, Wang Y#, Li L, Shi J, Liu J, Kong L, Yu L, Ding J, Huang Z*, Wang W*, Zhan C*. NIR Light-triggered Quantitative Pulsed Drug Release. Adv Healthc Mater 2022, 11(8):e2102362. (IF 9.93)
- Tang W#, Zhang Z#, Li C#, Chu Y, Qian J, Ying T*, Lu W*, Zhan C*. Facile Separation of PEGylated Liposomes Enabled by Anti-PEG scFv. Nano Lett 2021, 21(23):10107-10113. (IF 11.19)
- Yang M, Wu E, Tang W, Qian J, Zhan C*. Interplay between nanomedicines and protein corona. J Mater Chem B 2021, 9(34):6713-6727. (IF 6.33)
- Long K#, Yang Y#, Lv W, Jiang K, Li Y, Lo A, Lam W, Zhan C*, Wang W*. Green light-triggered intraocular drug release for intravenous chemotherapy of retinoblastoma. Adv Sci 2021: e2101754. (IF 16.81)
- Tian M, Xing R, Guan J, Yang B, Zhao X, Yang J, Zhan C*, Zhang S*. A Nanoantidote Alleviates Glioblastoma Chemotoxicity without Efficacy Compromise. Nano Lett 2021, 21(12):5158-5166. (IF 11.19)
- Jiang Z, Liu J, Guan J, Wang H, Ding T, Qian J*, Zhan C*. Self-adjuvant Effect by Manipulating Bio-nano Interface of Liposome-based Nanovaccines. Nano Lett 2021, 21(11):4744-52. (IF 11.19)
- Guan J#, Wu E#, Jin P, Hou S, Qian J, Lu W, Yu B, Zhan C*. Interrogating preclinical study of liposomes: The effect of mouse strain reexamined. J Control Release 2021, 334:178-187. (IF 9.78)
- Guan J#, Chen W#, Yang M, Wu E, Qian J, Zhan C*. Regulation of in vivo delivery of nanomedicines by herbal medicines. Adv Drug Deliv Rev 2021, 174: 210-228. (IF 15.47)
- Chu Y#, Tang W#, Zhang Z*, Li C, Qian J, Wei X, Ying T, Lu W, Zhan C*. Deciphering protein corona by scFv-based affinity chromatography. Nano Lett 2021, 21 (5): 2124-2131. (IF 11.19)
